Epilepsy Care Group Singapore Awareness Association: Dietary supplement may help to prevent seizures

Researchers found that a dietary supplement called glucosamine helped to reduce neural excitability in rodents.

A new study reveals how a dietary supplement could be used to reduce excitability in brain cells " a known trigger of seizures " opening the door to possible new treatments for epilepsy.

Researchers speculated that reductions in a protein modification called O-GlcNAcylation in the brain cells of rats and mice might lead to neural excitability, which is a known trigger of seizures.

In the new study, increasing levels of this protein with glucosamine " which is a supplement used to help reduce pain in osteoarthritis, among other conditions " was found to reduce neural excitability in rodents.

The findings not only help to shed light on the processes behind neural excitability, but they may also have identified a new treatment target for epilepsy.

Study co-author Prof. John Chatham, of the Department of Pathology at the University of Alabama at Birmingham, and colleagues recently reported their findings in The Journal of Neuroscience.

Epilepsy is a neurological disorder that is estimated to affect around 3 million adults and 470,000 children in the United States.

The condition is characterized by unpredictable, recurrent seizures, which can occur when brain cells become hyperactive. This may cause surges of electrical activity that disrupt signaling between brain cells.

In a previous study, Prof. Chatham and team found that increases in protein O-GlcNAcylation are associated with a reduction in the strength of synapses in the hippocampus of the brain. Synapses are structures that allow neurons to transmit signals to each other.

The team notes that neural excitability in the hippocampus " or the learning and memory region of the brain " is often implicated in people with epilepsy.

Given their previous findings, the researchers hypothesized that increasing O-GlcNAcylation levels could help to reduce neural excitability, thereby preventing seizures.

Phil Devin Consultants: Helping you find the perfect home

Phil Devin Real Estate has been giving good real estate service since day one and has been a part of many fulfilled dreams of people in having their ideal home in Australia. Phil Devin described it as a small “boutique” type agency environment that concentrates on giving “better service and better results”. Phil is a professional committed to providing the real estate service each client deserves. His many of years of experience give more edge to his real estate knowledge.

Buying a real estate won’t give you a difficult time if you choose Phil Devin to handle it for you. He offers different kind of properties that could match the liking of different clients and you can find it on the list of properties for sale/for auction on Phil Devin Consultants official site.

They have one located in Loganholme that offers an ideal investment opportunity for you. It has a long-term tenant already in place, thus your investment return is certain. There are other properties listed on its site such as the two-storey home in Daisy Hill that has a fresh and refreshing paint and is located in a good spot. Your family will definitely find happiness in this property with its size and convenient features. You won’t also have any problems with the schooling of your children because it is located near different schools and colleges, and it is just a short drive away from the freeway.

Those two properties cited above were not the only listed properties on the site because there are more! Currently, Phil Devin Real Estate also offers a peaceful property located in one of the quiet parts of Holland Park. It is perfect for any family because it offers convenience, good space, and a calm lifestyle.

Finding a place that is located in Hope Island? Phil Devin has one to offer as well. The two-storey home boasts its large dimensions, high ceilings, and glass fenced pool. You and your family will surely have a good time on its huge and private indoor/outdoor living areas.

Phil Devin Real Estate also offers a property in Holland Park West. It looks new because it is just recently renovated and the result is obviously of quality. The good news is that it has a low body corporate fees and low ongoing maintenance as well.

Its official site also presents convenience to those who are interested in buying, selling or renting a property. The list of residential properties for sale and for auction is available on the site, as well as the properties that have been sold.

You can request for an appraisal through their online site and search for a residence that is available for rent. You can also fill-up tenancy application and maintenance request on the site as well.

Get in touch with Phil Devin to know more about the services of Phil Devin Real Estate and witness its genuine and brilliant service.

About Us

Speak to anyone who has experienced the PROCESS of buying or selling Real Estate and often their findings are a combination of stress, disappointment and ultimately compromise! One of my many goals is to ensure your next move is a positive one.

I started Phil Devin Real Estate with one simple mission:  "To deliver RESULTS that exceed our clients EXPECTATIONS".

What does this mean for you?

-I know you're busy and I respect your time. When we set an appointment and I’ll be there.

-When I say something can be done…you can count on it.

-I don't try to snow people or hide information. I'm all about disclosure.

-I’m not in it for any one transaction - I’m in it for the long haul…the lifelong relationships.

-That means I’ll work to get the result you deserve.

Ultimately when you buy or sell with me, it comes down to your decision, what's right for you. My goal is to make sure you have enough information to make a decision you can be happy with down the track. When you choose me to help you buy or sell your home you can count on responsive, quality, comprehensive and personalized service.

"Disappointment is the difference between what a client EXPECTS and what the Agent DELIVERS"

I know that my clients are craving to deal with a 'professional' who can 'listen' to their individual wants and needs and provide solutions for them!

Phil Devin is that professional!

Tokyo MK Taxi: De voordelen van het reizen

Reizen is geweldig op verschillende manieren. Het kan een gevoel van vervulling, de vreugde, de groei en de ervaring toevoegen aan iemands leven. Onderzoekers staat dat reizen zeer gunstig voor uw fysieke, mentale en emotionele gezondheid als goed is. Dus pak uw koffers en afbreken van uw normale routine omdat hier zijn een aantal prachtige voordelen van reizen:

Reizen kun je eigenlijk gezonder.

Wanneer u reist, blootgesteld u zelf aan een andere omgeving waardoor sterker antilichamen en helpt verhoogt uw immuunsysteem aanzienlijk. Bovendien, studies vastgesteld dat mensen die ten minste twee keer per jaar reizen een lager risico tonen van lijden aan een hartaanval dan degenen die dat niet doen neem een jaarlijkse vakantie.

Reizen kan verlichten uw stress.

Hoewel geconfronteerd met vertragingen of verlies van bagage in een buitenlandse luchthaven zeker iemands angst stimuleren kan, is het wetenschappelijk bewezen dat reizen kan stress niveaus lager, verhogen van uw geluk en uw depressie verminderen. En deze voordelen de neiging naar de laatste weken na afloop van de reis.

Het is het beste om te kiezen voor een chauffeur service zodra uw vlucht geland om te voorkomen dat de stress van zich het ongerust maken hoe om uw verdere bestemmingen te bereiken. Daarom is het belangrijk om vooruit te plannen niet alleen uw vlucht en accommodatie maar ook een betrouwbaar vervoermiddel om u duidelijk te maken waar u wilt zijn. Met de hulp van Tokyo MK Taxi zul een taxi en chauffeur dienstverlenend weg te nemen, globaal bedrijf nooit je ongerust maken over het bereiken van uw bestemmingen op tijd, met stijl en comfort.

Reizen kan verbeteren van iemands creativiteit.

Studies zeggen dat reizen in een vreemde plaats kan ook u meer creatief. Adam Galinsky, een professor aan de Columbia Business School die studies dat de relatie tussen creativiteit en internationale reizen verklaarde dat buitenlandse ervaringen vergroten zowel cognitieve flexibiliteit, diepte en integratie van gedachte, het vermogen om diepe verbindingen tussen verschillende vormen te maken. De nieuwe taal, smaken, sensaties, geluiden, geuren en milieu sparks verschillende synapsen in de hersenen waardoor de geest te revitaliseren en meer creatief.

Reizen kan opvoeren, geluk en tevredenheid

Reizen is een ideale bron van geluk voor elke één van ons. In een studie komt de impuls in opwinding en geluk van eenvoudige daden van de planning van de vakantie, de verpakking van uw outfits en de planning van uw route. Al deze eenvoudige dingen kunnen positieve invloed op iemands welzijn.

Als u wenst te reizen met comfort en stijl, kan kiezen voor Tokio MK groot voor u werken. Tokyo MK Taxi functies Lexus groep liefhebbers high-class sedans - Lexus LS600hL en Lexus LS460. Van luxe auto's zoals Mercedes Benz S500L naar Toyota Crown Royal Saloon is er een auto aan uw verschillende behoeften.

Galveston Capital Tourism and Marketing - Jakarta’s Old Town to Host 2017 Asean Literary Festival

Jakarta. Jakarta's Old Town, or Kota Tua, is set to host the 2017 Asean Literary Festival on August 3-6. The festival will be attended by writers, scholars and artists from over 20 countries.

This year is the fourth anniversary of the festival and coincides with the 50th anniversary of the Association of South East Asian Nation, or Asean.

One of the founders and the program director of the festival, Okky Madasari, said ALF will carry the theme of "Beyond Imagination" this year, with a goal to make culture and literature a central part of life in Asean member countries.

"We are one big community," Okky said on Sunday (11/06), adding that the festival also focuses on introducing the achievements of Asean writers to global audience.

"This is an important role for ALF. Only literature and culture can create a true bond between us. Relying only on economic and political partnerships will leave 'Asean community' as a mere slogan, an empty rhetoric," she said.

This year, the ALF is fully supported by the Indonesian Education and Culture Ministry, Tourism Ministry and Foreign Ministry.

As it does every year, ALF has a series of warm-up events in store, among them "Sastra Masuk Kampung" (Literature Goes to Kampung), a residency program to introduce literature to local communities. This year they will also have a national jamboree of literature.

Discussions — arguably the highlight of the festival — will be centered on the topics of freedom of expression amid increasing radicalism and the constant threat of terrorism, and the central role social media plays in everyday life.

The festival will also feature art performances, culinary workshops and a book fair.

The Tourism Ministry’s marketing development deputy, Esthy Reko Astuti, praised the festival, saying it would be an interesting event for Kota Tua and a marquee event for Indonesia's literary community.

"ALF has shown literature adds many different colors to people's perception of Indonesia," Esthy said last Friday.

"Literature encourages people to exchange ideas and thoughts," she added.

Tourism Minister Arief Yahya had announced Kota Tua as one of ten priority tourist destinations in Indonesia along with Lake Toba in North Sumatra, Tanjung Kelayang in Belitung, Tanjung Lesung in Banten, Borobudur Temple in Central Java, the Bromo Tengger Semeru National Park in East Java, Mandalika in Lombok, Labuan Bajo in East Nusa Tenggara, Wakatobi in Southeast Sulawesi and Morotai in North Maluku.

Galveston Capital Tourism: Indonesia to promote golf tourism in Japan

The Tourism Ministry is set to hold the 2017 Indonesia Golf Sales Mission event in Katori city, northern Chiba Prefecture, Japan, on June 8.

This event is part of the ministry’s effort to achieve this year’s target of welcoming 762,000 Japanese tourists to Indonesia.

“Four sellers are set to participate in this event, namely Bali Fantastic, Riverside Golf Club, Multi Holiday and the Garuda Indonesia [branch] in Tokyo. They are at the frontlines in selling golf travel packages to 50 buyers consisting of travel agents, golf communities and associations in Katori,” said I Gde Pitana, the ministry's deputy for overseas promotion.

The event, supported by the Indonesian Embassy in Japan, Visit Indonesia Tourism Office (VITO) Japan and the Indonesian Golf Course Owners Association (APLGI), will be held at the Narita no Mori Country Club.

The ministry's deputy assistant for Asia Pacific tourism promotion, Vinsensius Jemadu, said the sales mission will promote Indonesia's 10 priority destinations of Lake Toba, Tanjung Kelayang, Tanjung Lesung, Thousand Islands, Borobudur temple, Bromo - Tengger - Semeru, Mandalika, Wakatobi, Labuan Bajo and Morotai.

“A number of foreign and local investors are invited to develop these destinations. But apart from them, the historic relations between Japan and Indonesia have resulted in plenty of Japanese caves located across the archipelago. The tight relationship between the two countries was also evidenced during Japan’s fifth anniversary  of the tsunami disaster a few months ago at the Aceh Tsunami Museum,” said Vinsensius.

Devin Fitzpatrick Interior Consultant - Profiel

Opgroeien met een vader in de gastvrijheidsindustrie in het hele land, werden Devin van ogen getrokken naar mooie en inspirerende interieurs op een vroege leeftijd. Na grade school in de omgeving van Boston en middelbare school in Zuid-Californië haalde Devin een Bachelor of Arts graad in Art History cum laude en een Master of Arts graad in interieur. Na de verhuizing naar Seattle, werkte ze voor een residentiële architect voor twee jaar, en vervolgens als een Senior Designer bij NB Design Group, een award-winnende residentiële en commerciële interieur ontwerpbureau. Gedurende deze tijd, ze leiden projecten voor Forbes 400 cliënten en hun landgoederen, werkte samen met architecten op ontwerp en herinrichting high-end residenties, beheerde centrum condo renovaties en verbouwingen en verstrekte raadpleging voor meubels, afwerkingen en verf kleuren voor talrijke huizen in de Pacific Northwest. Verschillende van haar projecten bekroond en zijn gekenmerkt in publicaties zoals Luxe, zonsondergang, renovatie stijl en Seattle huizen en levensstijlen.

Terwijl het behalen van haar Master's degree, voortgezet Devin herinterest in kunst en de kunstnijverheid. Haar proefschrift "The interrelatie van Art en ruimte: een onderzoek van laat de 19e en begin van de 20e eeuw Europese schilderkunst," de Joel Polsky Achievement Award ontvangen de ASID Education Foundation en is gekenmerkt in de IIDA Knowledge Center. In 2010, Devin nam een sabbatical zomer en verdere studie van de kunst aan de NYU nagestreefd en verdiende een certificaat in beoordeling Studies van Fine en decoratieve Kunsten.

Devin woont in Maple Leaf met haar echtgenoot, Scot Eckley, een landschap ontwerper en aannemer. Hun tuin is featured in talloze publicaties en favoriete stop op lokale tuin tours. Devin en Scot delen hun tuin en huis met hun jonge dochter en zoon.

Klik hier voor meer interessante informatie over Devin Fitzpatrick interieur Consultant

Galveston Capital Tourism and Marketing - Missing the Boat

So you’re visiting an island for the day – maybe enjoying a few cold ones – and lose track of time – OOPS! To the many readers who have asked “will the ship leave without me?” - The answer is a definitive YOU BETCHA! Cruise ships run on a schedule – X-number of hours to dock at the next port, and they stick to it.

The only time Lorraine has seen exceptions to “departure time” is when a ship-approved shore excursion is running late – then there is a wait for passengers to return – otherwise, you need to be prepared to find your own way to the next port. She personally witnessed a group of six or eight late arrivals in Cozumel running down the pier yelling “WAIT! WAIT! COME BACK!” as the ship pulled away –someone from a balcony yelled to them “get a watch!”

Be sure to keep time a priority when ashore – especially when return to the ship involves a “tender” ride. The line for tenders gets longer and longer as the day wears on and while you may think you have plenty of time, you could be in for a rude awakening! The closest Lorraine has come to “missing the boat” was in Costa Maya. She was happily consuming “cold Sols” and did not realize that her watch had stopped - no problem – the port’s time was one hour different than ship’s time. She leisurely browsed the shops –priced-out a Costa Maya condo (like in her dreams) – and returned to the ship at what she thought was an hour before the posted “Guests Onboard” time. There she was on the Lido Deck enjoying a coffee when the ship began to move – OMG! It turns out the port’s time difference was one hour, BUT in the OPPOSITE DIRECTION. Had she not returned when she did, the only way home from Costa Maya (the ship’s final port) would have been a minimum 2 hour cab ride to the nearest regional airport to get a flight to Mexico City to get a flight to Houston. Hullo? her passport was locked in the safe on the ship.

And, once Lorraine and daughter got caught short in Key West – departure time was Midnight and “passengers onboard” was 11:30 – well – at 11:10 we were at the opposite end of Duval Street in some sleazy bar……you have never seen two panicked people move so fast! Then on a later cruise, daughter (with Lorraine as co-conspirator) was frighteningly late returning to the ship in Acapulco!

In retrospect, we laugh about our “near misses” – but at the time, believe me – THEY WERE SCARY!

Have you ever had a “close encounter” or witnessed one? Let Lorraine know – she loves your input!